wehewehe kikoʻī
ʻO ke ala ʻike I o syphilis
ʻIke ʻia o Treponema pallidum IgM antibody
ʻO ka ʻike ʻana o Treponema pallidum IgM antibody he ala hou no ka ʻike ʻana i ka syphilis i nā makahiki i hala.ʻO ka antibody IgM he ʻano immunoglobulin, nona nā mea maikaʻi o ka naʻau kiʻekiʻe, ka ʻike mua, a me ka hoʻoholo ʻana i ka maʻi o ka pēpē me Treponema pallidum.ʻO ka hana ʻana o nā antibodies IgM kikoʻī ka pane mua o ke kino ma hope o ka maʻi me ka syphilis a me nā maʻi bacteria a i ʻole nā mea maʻi.He maikaʻi maʻamau i ka wā mua o ka maʻi.Hoʻonui ia me ka ulu ʻana o ka maʻi, a laila piʻi mālie ka antibody IgG.
Ma hope o ka hoʻomaʻamaʻa maikaʻi ʻana, nalowale ka antibody IgM a hoʻomau ka antibody IgG.Ma hope o ka mālama ʻana i ka penicillin, ua nalowale ʻo TP IgM i ka pae mua o nā maʻi syphilis me ka TP IgM maikaʻi.Ma hope o ka mālama ʻana i ka penicillin, ua nalowale nā mea maʻi TP IgM maikaʻi me nā syphilis lua i loko o 2 a 8 mau mahina.Eia kekahi, he mea koʻikoʻi ka ʻike ʻana o TP IgM no ka ʻike ʻana i ka syphilis congenital i nā neonates.No ka nui o ka molekele IgM antibody, ʻaʻole hiki i ka makuahine IgM antibody ke hele i loko o ka placenta.Inā maikaʻi ka TP IgM, ua maʻi ka pēpē.
ʻO ke ala ʻike syphilis II
Molecular biological detection
I nā makahiki i hala iho nei, ua ulu wikiwiki ka molecular biology, a ua hoʻohana nui ʻia ka ʻenehana PCR i ka hana lapaʻau.ʻO ka PCR i kapa ʻia he polymerase chain reaction, ʻo ia hoʻi, e hoʻonui i nā kaʻina DNA spirochete i koho ʻia mai nā mea i koho ʻia, i mea e hoʻonui ai i ka helu o nā kope spirochete DNA i koho ʻia, hiki ke hoʻomaʻamaʻa i ka ʻike me nā probes kikoʻī, a hoʻomaikaʻi i ka helu diagnostic.
Eia nō naʻe, pono kēia ʻano hoʻokolohua i kahi keʻena me nā kūlana maikaʻi loa a me nā ʻenehana papa mua, a he liʻiliʻi nā hale hana me ke kiʻekiʻe kiʻekiʻe ma Kina i kēia manawa.Inā ʻaʻole, inā he haumia, e kau ʻoe iā Treponema pallidum, a ma hope o ka hoʻonui ʻana o DNA, aia ʻo Escherichia coli, kahi e kaumaha ai ʻoe.Ke hahai pinepine nei kekahi mau keʻena liʻiliʻi i ke ʻano.Kau lākou i kahi hōʻailona o ka hale hana PCR a ʻai a inu pū, hiki ke hoʻopunipuni iā ia iho.ʻO ka ʻoiaʻiʻo, ʻaʻole pono ka ʻike o ka syphilis i ka PCR, akā ʻo ka hoʻāʻo ʻana i ke koko.