HEV(CMIA)

ʻO ke ala hoʻouna o ka maʻi hepatitis E (ma ke ala fecal oral route) a me nā hōʻike hōʻike (ka maʻi recessive, acute hepatitis, ʻaʻohe maʻi hepatitis a me nā mea ʻē aʻe) ua like ia me ka maʻi hepatitis A. He kiʻekiʻe ka nui o ka maʻi hepatitis E i ka poʻe ʻōpio a me nā poʻe makua 15-39 makahiki.ʻO ka maʻi Hepatitis E kekahi maʻi i kaupalena ʻia.ʻAʻohe hopena pathological pololei (CPE) ma ka hepatocytes.Hiki i ke kino ke loa'a i kekahi mau palekana ma hope o ka ma'i, akā 'a'ole lawa ka pa'a.Aia ka ma'i hepatitis E, a me na hana e pale aku ai i ka ma'i hepa E, o ke oki ana i ke ala lawe waha fecal.

Hoʻokuʻu ʻia ʻo HEV me nā feces o ka poʻe maʻi, hoʻolaha ʻia ma o ka pili ʻana i ke ola o kēlā me kēia lā, a hiki ke hoʻolaha ʻia a i ʻole ka maʻi maʻi maʻi ma muli o ka meaʻai a me nā kumu wai.ʻO ke kiʻekiʻe o ka maʻi maʻamau i ke kau ua a i ʻole ma hope o ke kahe ʻana.ʻO ka manawa incubation he 2-11 mau wiki, me ka awelika o 6 mau pule.ʻO ka hapa nui o nā poʻe maʻi maʻi he maʻi hepaʻa haʻahaʻa a haʻahaʻa, hoʻopaʻa pinepine iā lākou iho, a ʻaʻole ulu i HEV mau.Hoʻopilikia nui ia i nā ʻōpio makua, ʻoi aku ma mua o 65% o ia mau mea i loaʻa i ka pūʻulu makahiki o 16 a 19 mau makahiki, a ʻoi aku ka nui o nā maʻi subclinical i nā keiki.

ʻOi aku ka nui o ka make o ka poʻe mākua ma mua o ka maʻi hepatitis A, ʻoi aku ka nui o nā wahine hāpai i loaʻa i ka maʻi hepatitis E, a ʻo ka nui o ka make o ka maʻi i nā mahina ʻekolu i hala o ka hāpai ʻana he 20%.
Ma hope o ka maʻi HEV, hiki iā ia ke hana i ka pale pale pale e pale aku i ka maʻi HEV o ka maʻi like ʻole a i ʻole nā ​​​​ʻano like ʻole.Ua hōʻike ʻia ʻo antibody anti HEV i ka serum o ka hapa nui o nā maʻi ma hope o ka hoʻoponopono hou ʻana e mau ana no 4-14 mau makahiki.
No ka hoʻokolohua hoʻokolohua, hiki ke ʻike ʻia nā ʻāpana virus mai nā feces e ka microscope electron, hiki ke ʻike ʻia ka HEV RNA i loko o ka fecal bile e RT-PCR, a hiki ke ʻike ʻia nā antibodies anti HEV IgM a me IgG i loko o ka serum e ELISA me ka hoʻohana ʻana i ka recombinant HEV glutathione S-transferase fusion protein e like me antigen.
ʻO ka pale maʻamau o ka maʻi hepa E like nō ia me ka maʻi hepa B. ʻAʻole pono nā immunoglobulin maʻamau no ka lāʻau lapaʻau passive pilikia.